United MSD Foundation | Multiple Sulfatase Deficiency

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Finding a Treatment

Join the team committed to finding a treatment for MSD.

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Bespoke Award

A Public-Private Partnership

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Cheers to 10

$10 for 10 – Monthly Giving for a Decade of Real Progress

Give to celebrate the Power of 10 years!

MSD Virtual Summit

September 18-19, 2026: In Partnership, We Thrive

Together We Can Cure MSD

A young child with MSD named Willow laughing at Beach

Founded in 2016, United MSD Foundation is a registered 501(c)(3) nonprofit organization serving an international community of Multiple Sulfatase Deficiency families, researchers, and care providers. We exist to bring awareness to MSD, fund research toward treatment, and support families through education, resources, and community.

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What is MSD?

Multiple Sulfatase Deficiency (MSD) is a rare genetic, progressive, neurodegenerative disease caused by the build up of cellular waste throughout the body leading to neurologic regression and multisystemic symptoms.

MSD 101

A mother and her child with MSD embracing

1 in 500,000

Individuals are estimated to be affected by MSD worldwide

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23 Countries

Represent the families we have supported since 2016

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$1.2 million

Has funded critical research projects

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The Faces of MSD

Michał is a very joyful child. He loves watching cars, excavators and other mechanical equipment in action, especially when he can play with his toys. He likes animals very much. One of his favorite activities with his parents, Gabi and Robert, is reading books together and pointing out his favorite pictures. Even though times like these can be difficult, knowing what lies ahead, the Ryczek family does not lose hope….

Meet Michał

Madeleine is a joyful and loving little girl who enjoys playing with her toy cars, airplanes, dolls, and cozy movie days watching Toy Story and Shrek. Whether she’s singing and dancing at church or proudly attending Kindergarten, Mady’s upbeat nature shines with kindness, resilience, and determination— never letting MSD define her spirit or her ability to connect with others.

Meet Mady

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Let’s Connect

Connect with MSD families and get valuable information from medical researchers and doctors.

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For Families

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For Professionals